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Cryptotanshinone inhibits proliferation and induces apoptosis of breast cancer MCF-7 cells via GPER mediated PI3K/AKT signaling pathway

G protein-coupled estrogen receptor (GPER) was reported to be a potential target in the breast cancer therapy. This study aimed to illuminate the function of GPER and its mediated PI3K/AKT pathway in cryptotanshinone (CPT) inducing cell apoptosis and antiproliferation effect on GPER positive breast...

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Detalles Bibliográficos
Autores principales: Shi, Danning, Li, Hongbo, Zhang, Zeye, He, Yueshuang, Chen, Meng, Sun, Liping, Zhao, Piwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782479/
https://www.ncbi.nlm.nih.gov/pubmed/35061800
http://dx.doi.org/10.1371/journal.pone.0262389