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Cryptotanshinone inhibits proliferation and induces apoptosis of breast cancer MCF-7 cells via GPER mediated PI3K/AKT signaling pathway
G protein-coupled estrogen receptor (GPER) was reported to be a potential target in the breast cancer therapy. This study aimed to illuminate the function of GPER and its mediated PI3K/AKT pathway in cryptotanshinone (CPT) inducing cell apoptosis and antiproliferation effect on GPER positive breast...
Autores principales: | Shi, Danning, Li, Hongbo, Zhang, Zeye, He, Yueshuang, Chen, Meng, Sun, Liping, Zhao, Piwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782479/ https://www.ncbi.nlm.nih.gov/pubmed/35061800 http://dx.doi.org/10.1371/journal.pone.0262389 |
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