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Molecular basis of Arginine and Lysine DNA sequence-dependent thermo-stability modulation

We have used a variety of theoretical and experimental techniques to study the role of four basic amino acids–Arginine, Lysine, Ornithine and L-2,4-Diaminobutyric acid–on the structure, flexibility and sequence-dependent stability of DNA. We found that the presence of organic ions stabilizes the dup...

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Detalles Bibliográficos
Autores principales: Martin, Benjamin, Dans, Pablo D., Wieczór, Milosz, Villegas, Nuria, Brun-Heath, Isabelle, Battistini, Federica, Terrazas, Montserrat, Orozco, Modesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782489/
https://www.ncbi.nlm.nih.gov/pubmed/35007284
http://dx.doi.org/10.1371/journal.pcbi.1009749