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Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins

The complement system is a first-line innate host immune defence against invading pathogens. It is activated via three pathways, termed Classical, Lectin and Alternative, which are mediated by antibodies, carbohydrate arrays or microbial liposaccharides, respectively. The three complement pathways c...

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Detalles Bibliográficos
Autores principales: De Marco Verissimo, Carolina, Jewhurst, Heather L., Dobó, József, Gál, Péter, Dalton, John P., Cwiklinski, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782513/
https://www.ncbi.nlm.nih.gov/pubmed/35007288
http://dx.doi.org/10.1371/journal.ppat.1010226