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Epstein-Barr Virus BGLF2 commandeers RISC to interfere with cellular miRNA function

The Epstein-Barr virus (EBV) BGLF2 protein is a tegument protein with multiple effects on the cellular environment, including induction of SUMOylation of cellular proteins. Using affinity-purification coupled to mass-spectrometry, we identified the miRNA-Induced Silencing Complex (RISC), essential f...

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Detalles Bibliográficos
Autores principales: Campbell, Ashley M., De La Cruz-Herrera, Carlos F., Marcon, Edyta, Greenblatt, Jack, Frappier, Lori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782528/
https://www.ncbi.nlm.nih.gov/pubmed/35007297
http://dx.doi.org/10.1371/journal.ppat.1010235