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Capsaicin restores sodium iodine symporter-mediated radioiodine uptake through bypassing canonical TSH‒TSHR pathway in anaplastic thyroid carcinoma cells

Anaplastic thyroid cancer (ATC) is a rare but highly lethal disease. ATCs are resistant to standard therapies and are extremely difficult to manage. The stepwise cell dedifferentiation results in the impairment of the iodine-metabolizing machinery and the infeasibility of radioiodine treatment in AT...

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Detalles Bibliográficos
Autores principales: Xu, Shichen, Cheng, Xian, Wu, Jing, Wang, Yunping, Wang, Xiaowen, Wu, Liying, Yu, Huixin, Bao, Jiandong, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782610/
https://www.ncbi.nlm.nih.gov/pubmed/34751390
http://dx.doi.org/10.1093/jmcb/mjab072