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Systematic review on the application of machine learning to quantitative structure–activity relationship modeling against Plasmodium falciparum

Malaria accounts for over two million deaths globally. To flatten this curve, there is a need to develop new and high potent drugs against Plasmodium falciparum. Some major challenges include the dearth of suitable animal models for anti-P. falciparum assays, resistance to first-line drugs, lack of...

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Detalles Bibliográficos
Autores principales: Oguike, Osondu Everestus, Ugwuishiwu, Chikodili Helen, Asogwa, Caroline Ngozi, Nnadi, Charles Okeke, Obonga, Wilfred Ofem, Attama, Anthony Amaechi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782692/
https://www.ncbi.nlm.nih.gov/pubmed/35064444
http://dx.doi.org/10.1007/s11030-022-10380-1