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Systematic review on the application of machine learning to quantitative structure–activity relationship modeling against Plasmodium falciparum
Malaria accounts for over two million deaths globally. To flatten this curve, there is a need to develop new and high potent drugs against Plasmodium falciparum. Some major challenges include the dearth of suitable animal models for anti-P. falciparum assays, resistance to first-line drugs, lack of...
Autores principales: | Oguike, Osondu Everestus, Ugwuishiwu, Chikodili Helen, Asogwa, Caroline Ngozi, Nnadi, Charles Okeke, Obonga, Wilfred Ofem, Attama, Anthony Amaechi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782692/ https://www.ncbi.nlm.nih.gov/pubmed/35064444 http://dx.doi.org/10.1007/s11030-022-10380-1 |
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