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T cell apoptosis characterizes severe Covid-19 disease

Severe SARS-CoV-2 infections are characterized by lymphopenia, but the mechanisms involved are still elusive. Based on our knowledge of HIV pathophysiology, we hypothesized that SARS-CoV-2 infection-mediated lymphopenia could also be related to T cell apoptosis. By comparing intensive care unit (ICU...

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Detalles Bibliográficos
Autores principales: André, Sonia, Picard, Morgane, Cezar, Renaud, Roux-Dalvai, Florence, Alleaume-Butaux, Aurélie, Soundaramourty, Calaiselvy, Cruz, André Santa, Mendes-Frias, Ana, Gotti, Clarisse, Leclercq, Mickaël, Nicolas, Alexandre, Tauzin, Alexandra, Carvalho, Alexandre, Capela, Carlos, Pedrosa, Jorge, Castro, António Gil, Kundura, Lucy, Loubet, Paul, Sotto, Albert, Muller, Laurent, Lefrant, Jean-Yves, Roger, Claire, Claret, Pierre-Géraud, Duvnjak, Sandra, Tran, Tu-Anh, Racine, Gina, Zghidi-Abouzid, Ouafa, Nioche, Pierre, Silvestre, Ricardo, Droit, Arnaud, Mammano, Fabrizio, Corbeau, Pierre, Estaquier, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782710/
https://www.ncbi.nlm.nih.gov/pubmed/35066575
http://dx.doi.org/10.1038/s41418-022-00936-x