Cargando…
T cell apoptosis characterizes severe Covid-19 disease
Severe SARS-CoV-2 infections are characterized by lymphopenia, but the mechanisms involved are still elusive. Based on our knowledge of HIV pathophysiology, we hypothesized that SARS-CoV-2 infection-mediated lymphopenia could also be related to T cell apoptosis. By comparing intensive care unit (ICU...
Autores principales: | André, Sonia, Picard, Morgane, Cezar, Renaud, Roux-Dalvai, Florence, Alleaume-Butaux, Aurélie, Soundaramourty, Calaiselvy, Cruz, André Santa, Mendes-Frias, Ana, Gotti, Clarisse, Leclercq, Mickaël, Nicolas, Alexandre, Tauzin, Alexandra, Carvalho, Alexandre, Capela, Carlos, Pedrosa, Jorge, Castro, António Gil, Kundura, Lucy, Loubet, Paul, Sotto, Albert, Muller, Laurent, Lefrant, Jean-Yves, Roger, Claire, Claret, Pierre-Géraud, Duvnjak, Sandra, Tran, Tu-Anh, Racine, Gina, Zghidi-Abouzid, Ouafa, Nioche, Pierre, Silvestre, Ricardo, Droit, Arnaud, Mammano, Fabrizio, Corbeau, Pierre, Estaquier, Jérôme |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782710/ https://www.ncbi.nlm.nih.gov/pubmed/35066575 http://dx.doi.org/10.1038/s41418-022-00936-x |
Ejemplares similares
-
Low quantity and quality of anti-spike humoral response is linked to CD4 T-cell apoptosis in COVID-19 patients
por: André, Sonia, et al.
Publicado: (2022) -
Repetitive mRNA vaccination is required to improve the quality of broad-spectrum anti–SARS-CoV-2 antibodies in the absence of CXCL13
por: Azarias Da Silva, Marne, et al.
Publicado: (2023) -
Early ART reduces viral seeding and innate immunity in liver and lungs of SIV-infected macaques
por: Clain, Julien A., et al.
Publicado: (2023) -
Low perforin expression in CD8+ T lymphocytes during the acute phase of severe SARS-CoV-2 infection predicts long COVID
por: Kundura, Lucy, et al.
Publicado: (2022) -
Lipid metabolic reprogramming of hepatic CD4(+) T cells during SIV infection
por: Clain, Julien A., et al.
Publicado: (2023)