Mitotic phosphorylation of tumor suppressor DAB2IP maintains spindle assembly checkpoint and chromosomal stability through activating PLK1-Mps1 signal pathway and stabilizing mitotic checkpoint complex

Chromosomal instability (CIN) is a driving force for cancer development. The most common causes of CIN include the dysregulation of the spindle assembly checkpoint (SAC), which is a surveillance mechanism that prevents premature chromosome separation during mitosis by targeting anaphase-promoting co...

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Detalles Bibliográficos
Autores principales: Yu, Lan, Lang, Yue, Hsu, Ching-Cheng, Chen, Wei-Min, Chiang, Jui-Chung, Hsieh, Jer-Tsong, Story, Michael D., Shang, Zeng-Fu, Chen, Benjamin P. C., Saha, Debabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782720/
https://www.ncbi.nlm.nih.gov/pubmed/34775484
http://dx.doi.org/10.1038/s41388-021-02106-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782720/
https://www.ncbi.nlm.nih.gov/pubmed/34775484
http://dx.doi.org/10.1038/s41388-021-02106-8

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