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Multicomponent double Mannich alkylamination involving C(sp(2))–H and benzylic C(sp(3))–H bonds
Alkylamines are ubiquitous in pharmaceuticals, materials and agrochemicals. The Mannich reaction is a well-known three-component reaction for preparing alkylamines and has been widely used in academic research and industry. However, the nucleophilic components in this process rely on C(sp(2))−H and...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782832/ https://www.ncbi.nlm.nih.gov/pubmed/35064111 http://dx.doi.org/10.1038/s41467-022-28088-z |