Genome-wide detection of CRISPR editing in vivo using GUIDE-tag

Analysis of off-target editing is an important aspect of the development of safe nuclease-based genome editing therapeutics. in vivo assessment of nuclease off-target activity has primarily been indirect (based on discovery in vitro, in cells or via computational prediction) or through ChIP-based de...

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Detalles Bibliográficos
Autores principales: Liang, Shun-Qing, Liu, Pengpeng, Smith, Jordan L., Mintzer, Esther, Maitland, Stacy, Dong, Xiaolong, Yang, Qiyuan, Lee, Jonathan, Haynes, Cole M., Zhu, Lihua Julie, Watts, Jonathan K., Sontheimer, Erik J., Wolfe, Scot A., Xue, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782884/
https://www.ncbi.nlm.nih.gov/pubmed/35064134
http://dx.doi.org/10.1038/s41467-022-28135-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782884/
https://www.ncbi.nlm.nih.gov/pubmed/35064134
http://dx.doi.org/10.1038/s41467-022-28135-9

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