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GABA(A) and NMDA receptor density alterations and their behavioral correlates in the gestational methylazoxymethanol acetate model for schizophrenia

Hippocampal hyperactivity driven by GABAergic interneuron deficits and NMDA receptor hypofunction is associated with the hyperdopaminergic state often observed in schizophrenia. Furthermore, previous research in the methylazoxymethanol acetate (MAM) rat model has demonstrated that repeated peripuber...

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Detalles Bibliográficos
Autores principales: Kiemes, Amanda, Gomes, Felipe V., Cash, Diana, Uliana, Daniela L., Simmons, Camilla, Singh, Nisha, Vernon, Anthony C., Turkheimer, Federico, Davies, Cathy, Stone, James M., Grace, Anthony A., Modinos, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782908/
https://www.ncbi.nlm.nih.gov/pubmed/34743200
http://dx.doi.org/10.1038/s41386-021-01213-0