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CXCL12/CXCR4 axis supports mitochondrial trafficking in tumor myeloma microenvironment

Mesenchymal stromal cells (MSCs) within the protective microenvironment of multiple myeloma (MM) promote tumor growth, confer chemoresistance and support metabolic needs of plasma cells (PCs) even transferring mitochondria. In this scenario, heterocellular communication and dysregulation of critical...

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Detalles Bibliográficos
Autores principales: Giallongo, Cesarina, Dulcamare, Ilaria, Tibullo, Daniele, Del Fabro, Vittorio, Vicario, Nunzio, Parrinello, Nunziatina, Romano, Alessandra, Scandura, Grazia, Lazzarino, Giacomo, Conticello, Concetta, Li Volti, Giovanni, Amorini, Angela Maria, Musumeci, Giuseppe, Di Rosa, Michelino, Polito, Francesca, Oteri, Rosaria, Aguennouz, M’hammed, Parenti, Rosalba, Di Raimondo, Francesco, Palumbo, Giuseppe A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782911/
https://www.ncbi.nlm.nih.gov/pubmed/35064098
http://dx.doi.org/10.1038/s41389-022-00380-z