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Ex vivo anticoagulants affect human blood platelet biomechanics with implications for high-throughput functional mechanophenotyping

Inherited platelet disorders affecting the human platelet cytoskeleton result in increased bleeding risk. However, deciphering their impact on cytoskeleton-dependent intrinsic biomechanics of platelets remains challenging and represents an unmet need from a diagnostic and prognostic perspective. It...

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Detalles Bibliográficos
Autores principales: Sachs, Laura, Wesche, Jan, Lenkeit, Lea, Greinacher, Andreas, Bender, Markus, Otto, Oliver, Palankar, Raghavendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782918/
https://www.ncbi.nlm.nih.gov/pubmed/35064207
http://dx.doi.org/10.1038/s42003-021-02982-6