Metabolic adjustments of blood-stage Plasmodium falciparum in response to sublethal pyrazoleamide exposure

Due to the recurring loss of antimalarial drugs to resistance, there is a need for novel targets, drugs, and combination therapies to ensure the availability of current and future countermeasures. Pyrazoleamides belong to a novel class of antimalarial drugs that disrupt sodium ion homeostasis, altho...

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Detalles Bibliográficos
Autores principales: Tewari, Shivendra G., Kwan, Bobby, Elahi, Rubayet, Rajaram, Krithika, Reifman, Jaques, Prigge, Sean T., Vaidya, Akhil B., Wallqvist, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782945/
https://www.ncbi.nlm.nih.gov/pubmed/35064153
http://dx.doi.org/10.1038/s41598-022-04985-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782945/
https://www.ncbi.nlm.nih.gov/pubmed/35064153
http://dx.doi.org/10.1038/s41598-022-04985-7

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