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Metabolic adjustments of blood-stage Plasmodium falciparum in response to sublethal pyrazoleamide exposure
Due to the recurring loss of antimalarial drugs to resistance, there is a need for novel targets, drugs, and combination therapies to ensure the availability of current and future countermeasures. Pyrazoleamides belong to a novel class of antimalarial drugs that disrupt sodium ion homeostasis, altho...
Autores principales: | Tewari, Shivendra G., Kwan, Bobby, Elahi, Rubayet, Rajaram, Krithika, Reifman, Jaques, Prigge, Sean T., Vaidya, Akhil B., Wallqvist, Anders |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782945/ https://www.ncbi.nlm.nih.gov/pubmed/35064153 http://dx.doi.org/10.1038/s41598-022-04985-7 |
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