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Optogenetic stimulation of lateral hypothalamic orexin/dynorphin inputs in the ventral tegmental area potentiates mesolimbic dopamine neurotransmission and promotes reward-seeking behaviours

Reward and reinforcement processes are critical for survival and propagation of genes. While numerous brain systems underlie these processes, a cardinal role is ascribed to mesolimbic dopamine. However, ventral tegmental area (VTA) dopamine neurons receive complex innervation and various neuromodula...

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Detalles Bibliográficos
Autores principales: Thomas, Catherine S., Mohammadkhani, Aida, Rana, Madiha, Qiao, Min, Baimel, Corey, Borgland, Stephanie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782948/
https://www.ncbi.nlm.nih.gov/pubmed/34663867
http://dx.doi.org/10.1038/s41386-021-01196-y