HERC3 regulates epithelial-mesenchymal transition by directly ubiquitination degradation EIF5A2 and inhibits metastasis of colorectal cancer

E3 ligase is widely reported to exert fundamental functions in cancers. Through rigorous bioinformatic analysis concentrating E3 ligases based on data from Genotype-Tissue Expression (GTEx) and data from The Cancer Genome Atlas (TCGA), HERC3 was indicated to be downregulated in colorectal cancer (CR...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiyuan, He, Guodong, Lv, Yang, Liu, Yu, Niu, Zhengchuan, Feng, Qingyang, Hu, Ronggui, Xu, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782983/
https://www.ncbi.nlm.nih.gov/pubmed/35064108
http://dx.doi.org/10.1038/s41419-022-04511-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782983/
https://www.ncbi.nlm.nih.gov/pubmed/35064108
http://dx.doi.org/10.1038/s41419-022-04511-7

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