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Two distinct Notch signals, Delta-like 4/Notch1 and Jagged-1/Notch2, antagonistically regulate chemical hepatocarcinogenesis in mice

Notch signaling is one of the most common drivers of carcinogenesis in many types of cancers, including hepatocellular carcinoma (HCC); however, it occasionally suppresses tumor progression. Moreover, it is virtually unknown how different sets of Notch ligands and receptors regulate the HCC developm...

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Detalles Bibliográficos
Autores principales: Nakano, Yasuhiro, Nakao, Sachie, Sueoka, Minako, Kasahara, Daigo, Tanno, Yuri, Sumiyoshi, Hideaki, Itoh, Tohru, Miyajima, Atsushi, Hozumi, Katsuto, Inagaki, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782997/
https://www.ncbi.nlm.nih.gov/pubmed/35064244
http://dx.doi.org/10.1038/s42003-022-03013-8