An autonomous TCR signal-sensing switch influences CD4/CD8 lineage choice in mice

How multipotential cells initiate distinct gene expression programs in response to external cues to instruct cell fate choice remains a fundamental question in biology. Establishment of CD4 and CD8 T cell fates during thymocyte development is critically regulated by T cell receptor (TCR) signals, wh...

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Detalles Bibliográficos
Autores principales: Basu, Jayati, Zha, Jikun, Nicolas, Emmanuelle, Coulton, Michael, Czyzewicz, Philip, Hua, Xiang, Ge, Lu, Kappes, Dietmar J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783009/
https://www.ncbi.nlm.nih.gov/pubmed/35064205
http://dx.doi.org/10.1038/s42003-022-02999-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783009/
https://www.ncbi.nlm.nih.gov/pubmed/35064205
http://dx.doi.org/10.1038/s42003-022-02999-5

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