Massively parallel characterization of engineered transcript isoforms using direct RNA sequencing

Transcriptional terminators signal where transcribing RNA polymerases (RNAPs) should halt and disassociate from DNA. However, because termination is stochastic, two different forms of transcript could be produced: one ending at the terminator and the other reading through. An ability to control the...

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Detalles Bibliográficos
Autores principales: Tarnowski, Matthew J., Gorochowski, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783025/
https://www.ncbi.nlm.nih.gov/pubmed/35064117
http://dx.doi.org/10.1038/s41467-022-28074-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783025/
https://www.ncbi.nlm.nih.gov/pubmed/35064117
http://dx.doi.org/10.1038/s41467-022-28074-5

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