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Massively parallel characterization of engineered transcript isoforms using direct RNA sequencing
Transcriptional terminators signal where transcribing RNA polymerases (RNAPs) should halt and disassociate from DNA. However, because termination is stochastic, two different forms of transcript could be produced: one ending at the terminator and the other reading through. An ability to control the...
Autores principales: | Tarnowski, Matthew J., Gorochowski, Thomas E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783025/ https://www.ncbi.nlm.nih.gov/pubmed/35064117 http://dx.doi.org/10.1038/s41467-022-28074-5 |
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