Nitroreduction of flutamide by Cunninghamella elegans NADPH: Cytochrome P450 reductase

The microbial model of mammalian drug metabolism, Cunninghamella elegans, has three cytochrome P450 reductase genes in its genome: g1631 (CPR_A), g4301 (CPR_B), and g7609 (CPR_C). The nitroreductase activity of the encoded enzymes was investigated via expression of the genes in the yeast Pichia past...

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Detalles Bibliográficos
Autores principales: Khan, Mohd Faheem, Murphy, Cormac D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783101/
https://www.ncbi.nlm.nih.gov/pubmed/35097225
http://dx.doi.org/10.1016/j.bbrep.2022.101209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783101/
https://www.ncbi.nlm.nih.gov/pubmed/35097225
http://dx.doi.org/10.1016/j.bbrep.2022.101209

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