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Nitroreduction of flutamide by Cunninghamella elegans NADPH: Cytochrome P450 reductase

The microbial model of mammalian drug metabolism, Cunninghamella elegans, has three cytochrome P450 reductase genes in its genome: g1631 (CPR_A), g4301 (CPR_B), and g7609 (CPR_C). The nitroreductase activity of the encoded enzymes was investigated via expression of the genes in the yeast Pichia past...

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Detalles Bibliográficos
Autores principales:	Khan, Mohd Faheem, Murphy, Cormac D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783101/ https://www.ncbi.nlm.nih.gov/pubmed/35097225 http://dx.doi.org/10.1016/j.bbrep.2022.101209

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