Targeting transgenic proteins to alpha granules for platelet-directed gene therapy

Platelets are anucleate blood cells that are shed from megakaryocytes (MKs) into the bloodstream to maintain hemostasis and promote wound healing after vascular injury. To carry out their functions, platelets become activated and release bioactive substances from their secretory granules. As alpha g...

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Detalles Bibliográficos
Autores principales: Woods, Vanessa M.A., Latorre-Rey, Lisette J., Schenk, Franziska, Rommel, Marcel G.E., Moritz, Thomas, Modlich, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783114/
https://www.ncbi.nlm.nih.gov/pubmed/35116189
http://dx.doi.org/10.1016/j.omtn.2021.12.038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783114/
https://www.ncbi.nlm.nih.gov/pubmed/35116189
http://dx.doi.org/10.1016/j.omtn.2021.12.038

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