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Narciclasine targets STAT3 via distinct mechanisms in tamoxifen-resistant breast cancer cells

STAT3 is constitutively activated in multiple malignant tumors. Compared with regular estrogen receptor (ER)-positive breast cancers, the patients with tamoxifen-resistant breast cancers often exhibit higher levels of STAT3 phosphorylation. Narciclasine (Nar) possesses strong inhibiting effects agai...

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Detalles Bibliográficos
Autores principales: Lv, Chao, Huang, Yun, Huang, Rui, Wang, Qun, Zhang, Hongwei, Jin, Jinmei, Lu, Dong, Zhou, Yudong, Shen, Yunheng, Zhang, Weidong, Luan, Xin, Liu, Sanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783118/
https://www.ncbi.nlm.nih.gov/pubmed/35118192
http://dx.doi.org/10.1016/j.omto.2021.12.025