Loss of H2R Signaling Disrupts Neutrophil Homeostasis and Promotes Inflammation-Associated Colonic Tumorigenesis in Mice

BACKGROUND & AIMS: We previously showed that histamine suppressed inflammation-associated colonic tumorigenesis through histamine type 2 receptor (H2R) signaling in mice. This study aimed to precisely elucidate the downstream effects of H2R activation in innate immune cells. METHODS: Analyses us...

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Detalles Bibliográficos
Autores principales: Shi, Zhongcheng, Mori-Akiyama, Yuko, Du, Wa, Fultz, Robert, Zhao, Yanling, Ruan, Wenly, Venable, Susan, Engevik, Melinda A., Versalovic, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783126/
https://www.ncbi.nlm.nih.gov/pubmed/34781022
http://dx.doi.org/10.1016/j.jcmgh.2021.11.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783126/
https://www.ncbi.nlm.nih.gov/pubmed/34781022
http://dx.doi.org/10.1016/j.jcmgh.2021.11.003

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