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Loratadine inhibits Staphylococcus aureus virulence and biofilm formation

There are no anti-virulence and anti-biofilm treatments for Staphylococcus aureus infection. We found that 25 μM loratadine inhibits S. aureus biofilm formation under static or flow-based conditions. Testing of loratadine effects on 255 clinical S. aureus strains with varying biofilm robustness show...

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Detalles Bibliográficos
Autores principales: Zheng, Jinxin, Shang, Yongpeng, Wu, Yang, Zhao, Yuxi, Chen, Zhong, Lin, Zhiwei, Li, Peiyu, Sun, Xiang, Xu, Guangjian, Wen, Zewen, Chen, Junwen, Wang, Yu, Wang, Zhanwen, Xiong, Yanpeng, Deng, Qiwen, Qu, Di, Yu, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783127/
https://www.ncbi.nlm.nih.gov/pubmed/35098100
http://dx.doi.org/10.1016/j.isci.2022.103731