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Loratadine inhibits Staphylococcus aureus virulence and biofilm formation
There are no anti-virulence and anti-biofilm treatments for Staphylococcus aureus infection. We found that 25 μM loratadine inhibits S. aureus biofilm formation under static or flow-based conditions. Testing of loratadine effects on 255 clinical S. aureus strains with varying biofilm robustness show...
Autores principales: | Zheng, Jinxin, Shang, Yongpeng, Wu, Yang, Zhao, Yuxi, Chen, Zhong, Lin, Zhiwei, Li, Peiyu, Sun, Xiang, Xu, Guangjian, Wen, Zewen, Chen, Junwen, Wang, Yu, Wang, Zhanwen, Xiong, Yanpeng, Deng, Qiwen, Qu, Di, Yu, Zhijian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783127/ https://www.ncbi.nlm.nih.gov/pubmed/35098100 http://dx.doi.org/10.1016/j.isci.2022.103731 |
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