Efficacy and Safety of Andexanet Alfa for Bleeding Caused by Factor Xa Inhibitors: A Systematic Review and Meta-Analysis

Direct oral anticoagulants (DOAC) including factor Xa inhibitors are associated with bleeding events which can lead to severe morbidity and mortality. Reversal agents like andexanet alfa (AA) and 4F-PCC (Four-factor prothrombin concentrate complex) are available for treating bleeding that occurs wit...

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Detalles Bibliográficos
Autores principales: Shrestha, Dhan B, Budhathoki, Pravash, Adhikari, Ayush, Shrestha, Sudat, Khati, Nirajan, Mir, Wasey Ali Yadullahi, Joshi, Tilak, Shrestha, Anuj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783383/
https://www.ncbi.nlm.nih.gov/pubmed/35103198
http://dx.doi.org/10.7759/cureus.20632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783383/
https://www.ncbi.nlm.nih.gov/pubmed/35103198
http://dx.doi.org/10.7759/cureus.20632

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