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Plasma FGF21 concentrations are regulated by glucose independently of insulin and GLP-1 in lean, healthy humans

BACKGROUND: Fibroblast growth factor 21 (FGF21) treatment improves metabolic homeostasis in diverse species, including humans. Physiologically, plasma FGF21 levels increase modestly after glucose ingestion, but it is unclear whether this is mediated by glucose itself or due to a secondary effect of...

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Detalles Bibliográficos
Autores principales: Solomon, Thomas P.J., Carter, Steven, Haus, Jacob M., Karstoft, Kristian, von Holstein-Rathlou, Stephanie, Nielsen, Mette S., Gillum, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783558/
https://www.ncbi.nlm.nih.gov/pubmed/35111398
http://dx.doi.org/10.7717/peerj.12755