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PD-1 blockade counteracts post–COVID-19 immune abnormalities and stimulates the anti–SARS-CoV-2 immune response

A substantial proportion of patients who have recovered from coronavirus disease-2019 (COVID-19) experience COVID-19–related symptoms even months after hospital discharge. We extensively immunologically characterized patients who recovered from COVID-19. In these patients, T cells were exhausted, wi...

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Detalles Bibliográficos
Autores principales: Loretelli, Cristian, Abdelsalam, Ahmed, D’Addio, Francesca, Ben Nasr, Moufida, Assi, Emma, Usuelli, Vera, Maestroni, Anna, Seelam, Andy Joe, Ippolito, Elio, Di Maggio, Stefania, Loreggian, Lara, Radovanovic, Dejan, Vanetti, Claudia, Yang, Jun, El Essawy, Basset, Rossi, Antonio, Pastore, Ida, Montefusco, Laura, Lunati, Maria Elena, Bolla, Andrea M., Biasin, Mara, Antinori, Spinello, Santus, Pierachille, Riva, Agostino, Zuccotti, Gian Vincenzo, Galli, Massimo, Rusconi, Stefano, Fiorina, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783674/
https://www.ncbi.nlm.nih.gov/pubmed/34784300
http://dx.doi.org/10.1172/jci.insight.146701