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Clinical importance of high-mannose, fucosylated, and complex N-glycans in breast cancer metastasis

BACKGROUND. Although aberrant glycosylation is recognized as a hallmark of cancer, glycosylation in clinical breast cancer (BC) metastasis has not yet been studied. While preclinical studies show that the glycocalyx coating of cancer cells is involved in adhesion, migration, and metastasis, glycosyl...

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Detalles Bibliográficos
Autores principales: Ščupáková, Klára, Adelaja, Oluwatobi T., Balluff, Benjamin, Ayyappan, Vinay, Tressler, Caitlin M., Jenkinson, Nicole M., Claes, Britt S.R., Bowman, Andrew P., Cimino-Mathews, Ashley M., White, Marissa J., Argani, Pedram, Heeren, Ron M.A., Glunde, Kristine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783675/
https://www.ncbi.nlm.nih.gov/pubmed/34752419
http://dx.doi.org/10.1172/jci.insight.146945