Intestinal epithelial glucocorticoid receptor promotes chronic inflammation–associated colorectal cancer

Synthetic immunosuppressive glucocorticoids (GCs) are widely used to control inflammatory bowel disease (IBD). However, the impact of GC signaling on intestinal tumorigenesis remains controversial. Here, we report that intestinal epithelial GC receptor (GR), but not whole intestinal tissue GR, promo...

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Detalles Bibliográficos
Autores principales: Tang, Shuang, Zhang, Zhan, Oakley, Robert H., Li, Wenling, He, Weijing, Xu, Xiaojiang, Ji, Ming, Xu, Qing, Chen, Liang, Wellman, Alicia S., Li, Qingguo, Li, Leping, Li, Jian-Liang, Li, Xinxiang, Cidlowski, John A., Li, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783679/
https://www.ncbi.nlm.nih.gov/pubmed/34784298
http://dx.doi.org/10.1172/jci.insight.151815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783679/
https://www.ncbi.nlm.nih.gov/pubmed/34784298
http://dx.doi.org/10.1172/jci.insight.151815

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