Cross-validation of SARS-CoV-2 responses in kidney organoids and clinical populations

Kidneys are critical target organs of COVID-19, but susceptibility and responses to infection remain poorly understood. Here, we combine SARS-CoV-2 variants with genome-edited kidney organoids and clinical data to investigate tropism, mechanism, and therapeutics. SARS-CoV-2 specifically infects orga...

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Detalles Bibliográficos
Autores principales: Helms, Louisa, Marchiano, Silvia, Stanaway, Ian B., Hsiang, Tien-Ying, Juliar, Benjamin A., Saini, Shally, Zhao, Yan Ting, Khanna, Akshita, Menon, Rajasree, Alakwaa, Fadhl, Mikacenic, Carmen, Morrell, Eric D., Wurfel, Mark M., Kretzler, Matthias, Harder, Jennifer L., Murry, Charles E., Himmelfarb, Jonathan, Ruohola-Baker, Hannele, Bhatraju, Pavan K., Gale, Michael, Freedman, Benjamin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783682/
https://www.ncbi.nlm.nih.gov/pubmed/34767537
http://dx.doi.org/10.1172/jci.insight.154882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783682/
https://www.ncbi.nlm.nih.gov/pubmed/34767537
http://dx.doi.org/10.1172/jci.insight.154882

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