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Maternal Western diet exposure increases periportal fibrosis beginning in utero in nonhuman primate offspring

Maternal obesity affects nearly one-third of pregnancies and is a major risk factor for nonalcoholic fatty liver disease (NAFLD) in adolescent offspring, yet the mechanisms behind NAFLD remain poorly understood. Here, we demonstrate that nonhuman primate fetuses exposed to maternal Western-style die...

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Detalles Bibliográficos
Autores principales: Nash, Michael J., Dobrinskikh, Evgenia, Newsom, Sean A., Messaoudi, Ilhem, Janssen, Rachel C., Aagaard, Kjersti M., McCurdy, Carrie E., Gannon, Maureen, Kievit, Paul, Friedman, Jacob E., Wesolowski, Stephanie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783685/
https://www.ncbi.nlm.nih.gov/pubmed/34935645
http://dx.doi.org/10.1172/jci.insight.154093