Cargando…

Single-cell profiling of T and B cell repertoires following SARS-CoV-2 mRNA vaccine

mRNA vaccines for SARS-CoV-2 have shown exceptional clinical efficacy, providing robust protection against severe disease. However, our understanding of transcriptional and repertoire changes following full vaccination remains incomplete. We used scRNA-Seq and functional assays to compare humoral an...

Descripción completa

Detalles Bibliográficos
Autores principales: Sureshchandra, Suhas, Lewis, Sloan A., Doratt, Brianna M., Jankeel, Allen, Coimbra Ibraim, Izabela, Messaoudi, Ilhem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783687/
https://www.ncbi.nlm.nih.gov/pubmed/34935643
http://dx.doi.org/10.1172/jci.insight.153201