Pregnancy-associated plasma protein A mRNA expression as a marker for differentiated thyroid cancer: results from a “surgical” and a “cytological” series

PURPOSE: Pregnancy-associated plasma protein A (PAPPA) is a metalloproteinase initially described for its role during pregnancy. PAPPA regulates IGF ligands 1 (IGF1) bioavailability through the degradation of IGF-binding protein 4 (IGFBP4). After the cleavage of IGFBP4, free IGF1 is able to bind IGF...

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Detalles Bibliográficos
Autores principales: Marzocchi, C., Capezzone, M., Sagnella, A., Cartocci, A., Caroli Costantini, M., Brindisi, L., Mancini, V., Cantara, S., Castagna, M. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783868/
https://www.ncbi.nlm.nih.gov/pubmed/34350538
http://dx.doi.org/10.1007/s40618-021-01655-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783868/
https://www.ncbi.nlm.nih.gov/pubmed/34350538
http://dx.doi.org/10.1007/s40618-021-01655-9

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