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T cells, particularly activated CD4(+) cells, maintain anti-CD20-mediated NK cell viability and antibody dependent cellular cytotoxicity

Anti-CD20 monoclonal antibody (mAb) therapy is a mainstay of therapy for B cell malignancies, however many patients fail to respond or eventually develop resistance. The current understanding of mechanisms responsible for this resistance is limited. When peripheral blood mononuclear cells of healthy...

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Detalles Bibliográficos
Autores principales: Wang, Zhaoming, Chimenti, Michael S., Strouse, Christopher, Weiner, George J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783893/
https://www.ncbi.nlm.nih.gov/pubmed/34110453
http://dx.doi.org/10.1007/s00262-021-02976-7