The two-stage interaction of Ebola virus VP40 with nucleoprotein results in a switch from viral RNA synthesis to virion assembly/budding

Ebola virus (EBOV) is an enveloped negative-sense RNA virus and a member of the filovirus family. Nucleoprotein (NP) expression alone leads to the formation of inclusion bodies (IBs), which are critical for viral RNA synthesis. The matrix protein, VP40, not only plays a critical role in virus assemb...

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Detalles Bibliográficos
Autores principales: Wu, Linjuan, Jin, Dongning, Wang, Dan, Jing, Xuping, Gong, Peng, Qin, Yali, Chen, Mingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783937/
https://www.ncbi.nlm.nih.gov/pubmed/33141416
http://dx.doi.org/10.1007/s13238-020-00764-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783937/
https://www.ncbi.nlm.nih.gov/pubmed/33141416
http://dx.doi.org/10.1007/s13238-020-00764-0

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