Cargando…

B cell–derived IL-27 promotes control of persistent LCMV infection

Recent studies have identified a critical role for B cell–produced cytokines in regulating both humoral and cellular immunity. Here, we show that B cells are an essential source of interleukin-27 (IL-27) during persistent lymphocytic choriomeningitis virus (LCMV) clone 13 (Cl-13) infection. By using...

Descripción completa

Detalles Bibliográficos
Autores principales: Pratumchai, Isaraphorn, Zak, Jaroslav, Huang, Zhe, Min, Booki, Oldstone, Michael B. A., Teijaro, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784116/
https://www.ncbi.nlm.nih.gov/pubmed/35022243
http://dx.doi.org/10.1073/pnas.2116741119