Reciprocal modulation of long noncoding RNA EMS and p53 regulates tumorigenesis

p53 plays a central role in tumor suppression. Emerging evidence suggests long noncoding RNA (lncRNA) as an important class of regulatory molecules that control the p53 signaling. Here, we report that the oncogenic lncRNA E2F1 messenger RNA (mRNA) stabilizing factor (EMS) and p53 mutually repress ea...

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Detalles Bibliográficos
Autores principales: Wang, Chenfeng, Yang, Yang, Wu, Xianning, Li, Jingxin, Liu, Kaiyue, Fang, Debao, Li, Bingyan, Shan, Ge, Mei, Xinyu, Wang, Fang, Mei, Yide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784137/
https://www.ncbi.nlm.nih.gov/pubmed/35022235
http://dx.doi.org/10.1073/pnas.2111409119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784137/
https://www.ncbi.nlm.nih.gov/pubmed/35022235
http://dx.doi.org/10.1073/pnas.2111409119

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