PET imaging and treatment of pancreatic cancer peritoneal carcinomatosis after subcutaneous intratumoral administration of a novel oncolytic virus, CF33-hNIS-antiPDL1

Peritoneal carcinomatosis of gastrointestinal malignancies remains fatal. CF33-hNIS-antiPDL1, a chimeric orthopoxvirus expressing the human sodium iodide symporter (hNIS) and anti-human programmed death-ligand 1 antibody, has demonstrated robust preclinical activity against pancreatic adenocarcinoma...

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Detalles Bibliográficos
Autores principales: Zhang, Zhifang, Yang, Annie, Chaurasiya, Shyambabu, Park, Anthony K., Kim, Sang-In, Lu, Jianming, Olafsen, Tove, Warner, Susanne G., Fong, Yuman, Woo, Yanghee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784298/
https://www.ncbi.nlm.nih.gov/pubmed/35118191
http://dx.doi.org/10.1016/j.omto.2021.12.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784298/
https://www.ncbi.nlm.nih.gov/pubmed/35118191
http://dx.doi.org/10.1016/j.omto.2021.12.022

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