Phenotyping clonal populations of glioma stem cell reveals a high degree of plasticity in response to changes of microenvironment

The phenotype of glioma-initiating cells (GIC) is modulated by cell-intrinsic and cell-extrinsic factors. Phenotypic heterogeneity and plasticity of GIC is an important limitation to therapeutic approaches targeting cancer stem cells. Plasticity also presents a challenge to the identification, isola...

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Detalles Bibliográficos
Autores principales: Innes, James A., Lowe, Andrew S., Fonseca, Raquel, Aley, Natasha, El-Hassan, Tedani, Constantinou, Myrianni, Lau, Joanne, Eddaoudi, Ayad, Marino, Silvia, Brandner, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784315/
https://www.ncbi.nlm.nih.gov/pubmed/34782726
http://dx.doi.org/10.1038/s41374-021-00695-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784315/
https://www.ncbi.nlm.nih.gov/pubmed/34782726
http://dx.doi.org/10.1038/s41374-021-00695-2

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