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Phenotyping clonal populations of glioma stem cell reveals a high degree of plasticity in response to changes of microenvironment
The phenotype of glioma-initiating cells (GIC) is modulated by cell-intrinsic and cell-extrinsic factors. Phenotypic heterogeneity and plasticity of GIC is an important limitation to therapeutic approaches targeting cancer stem cells. Plasticity also presents a challenge to the identification, isola...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group US
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784315/ https://www.ncbi.nlm.nih.gov/pubmed/34782726 http://dx.doi.org/10.1038/s41374-021-00695-2 |