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NAMPT mitigates colitis severity by supporting redox-sensitive activation of phagocytosis in inflammatory macrophages

Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme in the nicotinamide adenine dinucleotide (NAD(+)) salvage pathway and plays a crucial role in the maintenance of the NAD(+) pool during inflammation. Considering that macrophages are essential for tissue homeostasis and infla...

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Detalles Bibliográficos
Autores principales: Hong, Sun Mi, Lee, A-Yeon, Hwang, Sung-Min, Ha, Yu-Jin, Kim, Moo-Jin, Min, Seongki, Hwang, Won, Yoon, Gyesoon, Kwon, So Mee, Woo, Hyun Goo, Kim, Hee-Hoon, Jeong, Won-Il, Shen, Han-Ming, Im, Sin-Hyeog, Lee, Dakeun, Kim, You-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784331/
https://www.ncbi.nlm.nih.gov/pubmed/35063804
http://dx.doi.org/10.1016/j.redox.2022.102237