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NAMPT mitigates colitis severity by supporting redox-sensitive activation of phagocytosis in inflammatory macrophages
Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme in the nicotinamide adenine dinucleotide (NAD(+)) salvage pathway and plays a crucial role in the maintenance of the NAD(+) pool during inflammation. Considering that macrophages are essential for tissue homeostasis and infla...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784331/ https://www.ncbi.nlm.nih.gov/pubmed/35063804 http://dx.doi.org/10.1016/j.redox.2022.102237 |