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Interaction of DBC1 with polyoma small T antigen promotes its degradation and negatively regulates tumorigenesis

Deleted in Breast Cancer 1 (DBC1) is an important metabolic sensor. Previous studies have implicated DBC1 in various cellular functions, notably cell proliferation, apoptosis, histone modification, and adipogenesis. However, current reports about the role of DBC1 in tumorigenesis are controversial a...

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Detalles Bibliográficos
Autores principales: Sarwar, Zarka, Nabi, Nusrat, Bhat, Sameer Ahmed, Gillani, Syed Qaaifah, Reshi, Irfana, Un Nisa, Misbah, Adelmant, Guillaume, A. Marto, Jarrod, Andrabi, Shaida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784333/
https://www.ncbi.nlm.nih.gov/pubmed/34921839
http://dx.doi.org/10.1016/j.jbc.2021.101496