Involvement of FoxO1, Sp1, and Nrf2 in Upregulation of Negative Regulator of ROS by 15d-PGJ(2) Attenuates H(2)O(2)-Induced IL-6 Expression in Rat Brain Astrocytes

Excessive production of reactive oxygen species (ROS) by NADPH oxidase (Nox) resulted in inflammation. The negative regulator of ROS (NRROS) dampens ROS generation during inflammatory responses. 15-Deoxy-∆12,14-prostaglandin J(2) (15d-PGJ(2)) exhibits neuroprotective effects on central nervous syste...

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Detalles Bibliográficos
Autores principales: Wang, Chen-Yu, Yang, Chien-Chung, Hsiao, Li-Der, Yang, Chuen-Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784370/
https://www.ncbi.nlm.nih.gov/pubmed/34997457
http://dx.doi.org/10.1007/s12640-020-00318-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784370/
https://www.ncbi.nlm.nih.gov/pubmed/34997457
http://dx.doi.org/10.1007/s12640-020-00318-6

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